Decision
Local TMP-SMX susceptibility 80%-100%?
YES
TMP-SMX, 10-14 day course (Class II)
- No longer recommended in pregnancy
- If TMP-SMX allergic, use recommendation below ⬇
NO or UNKNOWN
Second generation (cefaclor) or third generation (cefpodoxime, cefdinir) cephalosporin PO, 10-14 day course (Class II)
Penicillin Allergy